DOPEY2

From Wikipedia, the free encyclopedia

Dopey family member 2

Identifiers

DOPEY2; C21orf5

External IDs

OMIM: 604803 MGI: 1917278 HomoloGene: 21068

Gene ontology
Molecular Function:	• molecular_function
Cellular Component:	• Golgi membrane
Biological Process:	• Golgi to endosome transport • endoplasmic reticulum organization and biogenesis • multicellular organismal development

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_005128 (mRNA)
NP_005119 (protein)

NM_026700 (mRNA)
NP_080976 (protein)

Location

Chr 21: 36.46 - 36.59 Mb

Chr 16: 93.6 - 93.7 Mb

Pubmed search

[1]

[2]

Dopey family member 2, also known as DOPEY2, is a human gene.^[1]

[edit] References

^ Entrez Gene: DOPEY2 dopey family member 2.

[edit] Further reading

Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. PMID 12168954.
Dahmane N, Ghezala GA, Gosset P, et al. (1998). "Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome.". Genomics 48 (1): 12–23. doi:10.1006/geno.1997.5146. PMID 9503011.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (1): 63–70. PMID 10231032.
Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21.". Nature 405 (6784): 311–9. doi:10.1038/35012518. PMID 10830953.
Pascon RC, Miller BL (2000). "Morphogenesis in Aspergillus nidulans requires Dopey (DopA), a member of a novel family of leucine zipper-like proteins conserved from yeast to humans.". Mol. Microbiol. 36 (6): 1250–64. PMID 10931277.
Guipponi M, Brunschwig K, Chamoun Z, et al. (2001). "C21orf5, a novel human chromosome 21 gene, has a Caenorhabditis elegans ortholog (pad-1) required for embryonic patterning.". Genomics 68 (1): 30–40. doi:10.1006/geno.2000.6250. PMID 10950924.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Lopes C, Chettouh Z, Delabar JM, Rachidi M (2003). "The differentially expressed C21orf5 gene in the medial temporal-lobe system could play a role in mental retardation in Down syndrome and transgenic mice.". Biochem. Biophys. Res. Commun. 305 (4): 915–24. PMID 12767918.
Rachidi M, Lopes C, Delezoide AL, Delabar JM (2006). "C21orf5, a human candidate gene for brain abnormalities and mental retardation in Down syndrome.". Cytogenet. Genome Res. 112 (1-2): 16–22. doi:10.1159/000087509. PMID 16276086.
Gillingham AK, Whyte JR, Panic B, Munro S (2006). "Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus.". J. Biol. Chem. 281 (4): 2273–80. doi:10.1074/jbc.M510176200. PMID 16301316.
Rachidi M, Lopes C, Costantine M, Delabar JM (2007). "C21orf5, a new member of Dopey family involved in morphogenesis, could participate in neurological alterations and mental retardation in Down syndrome.". DNA Res. 12 (3): 203–10. doi:10.1093/dnares/dsi004. PMID 16303751.