Dolichylphosphate-mannose phosphodiesterase

From Wikipedia, the free encyclopedia

In enzymology, a dolichylphosphate-mannose phosphodiesterase (EC 3.1.4.49) is an enzyme that catalyzes the chemical reaction

dolichyl beta-D-mannosyl phosphate + H₂O dolichyl phosphate + D-mannose

Thus, the two substrates of this enzyme are dolichyl beta-D-mannosyl phosphate and H₂O, whereas its two products are dolichyl phosphate and D-mannose.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is dolichyl-beta-D-mannosyl-phosphate dolichylphosphohydrolase. This enzyme is also called mannosylphosphodolichol phosphodiesterase.

[edit] References

• IUBMB entry for 3.1.4.49
• BRENDA references for 3.1.4.49 (Recommended.)
• PubMed references for 3.1.4.49
• PubMed Central references for 3.1.4.49
• Google Scholar references for 3.1.4.49
• Tomita Y, Motokawa Y (1987). "Characterization and partial purification of a novel mannosylphosphodolichol phosphodiesterase from chicken liver microsomes". Eur. J. Biochem. 170: 363–8. doi:10.1111/j.1432-1033.1987.tb13708.x. PMID 2826159. 

[edit] External links

The CAS registry number for this enzyme class is 111839-07-7.

• IUBMB entry for 3.1.4.49

• KEGG entry for 3.1.4.49

• BRENDA entry for 3.1.4.49

• NiceZyme view of 3.1.4.49

• EC2PDB: PDB structures for 3.1.4.49

• PRIAM entry for 3.1.4.49

• PUMA2 entry for 3.1.4.49

• IntEnz: Integrated Enzyme entry for 3.1.4.49

• MetaCyc entry for 3.1.4.49

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047398: dolichylphosphate-mannose phosphodiesterase

• AMIGO entry for GO code 0047398: dolichylphosphate-mannose phosphodiesterase