Dolichylphosphate-glucose phosphodiesterase

From Wikipedia, the free encyclopedia

In enzymology, a dolichylphosphate-glucose phosphodiesterase (EC 3.1.4.48) is an enzyme that catalyzes the chemical reaction

dolichyl beta-D-glucosyl phosphate + H₂O dolichyl phosphate + D-glucose

Thus, the two substrates of this enzyme are dolichyl beta-D-glucosyl phosphate and H₂O, whereas its two products are dolichyl phosphate and D-glucose.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase. Other names in common use include dolichol phosphoglucose phosphodiesterase, and Dol-P-Glc phosphodiesterase. This enzyme participates in n-glycan biosynthesis.

[edit] References

• IUBMB entry for 3.1.4.48
• BRENDA references for 3.1.4.48 (Recommended.)
• PubMed references for 3.1.4.48
• PubMed Central references for 3.1.4.48
• Google Scholar references for 3.1.4.48
• Crean EV (1984). "Synthesis and degradation of dolichyl phosphoryl glucose by the cellular slime mold, Dictyostelium discoideum". Biochim. Biophys. Acta 792: 149–157. 

[edit] External links

The CAS registry number for this enzyme class is 89287-42-3.

• IUBMB entry for 3.1.4.48

• KEGG entry for 3.1.4.48

• BRENDA entry for 3.1.4.48

• NiceZyme view of 3.1.4.48

• EC2PDB: PDB structures for 3.1.4.48

• PRIAM entry for 3.1.4.48

• PUMA2 entry for 3.1.4.48

• IntEnz: Integrated Enzyme entry for 3.1.4.48

• MetaCyc entry for 3.1.4.48

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047397: dolichylphosphate-glucose phosphodiesterase

• AMIGO entry for GO code 0047397: dolichylphosphate-glucose phosphodiesterase