Dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase

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In enzymology, a dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase (EC 2.4.1.130) is an enzyme that catalyzes the chemical reaction in which an alpha-D-mannosyl residue is transferred from a dolichyl-phosphate D-mannose molecule into a membrane lipid-linked oligosaccharide.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is dolichyl-phosphate-D-mannose:glycolipid alpha-D-mannosyltransferase. Other names in common use include dolichol phosphomannose-oligosaccharide-lipid mannosyltransferase, and oligomannosylsynthase. This enzyme participates in n-glycan biosynthesis and glycan structures - biosynthesis 1.

[edit] References

• IUBMB entry for 2.4.1.130
• BRENDA references for 2.4.1.130 (Recommended.)
• PubMed references for 2.4.1.130
• PubMed Central references for 2.4.1.130
• Google Scholar references for 2.4.1.130
• Rearick JI, Fujimoto K, Kornfeld S (1981). "Identification of the mannosyl donors involved in the synthesis of lipid-linked oligosaccharides". J. Biol. Chem. 256: 3762–9. PMID 6163773. 

[edit] External links

The CAS registry number for this enzyme class is 77967-76-1.

• IUBMB entry for 2.4.1.130

• KEGG entry for 2.4.1.130

• BRENDA entry for 2.4.1.130

• NiceZyme view of 2.4.1.130

• EC2PDB: PDB structures for 2.4.1.130

• PRIAM entry for 2.4.1.130

• PUMA2 entry for 2.4.1.130

• IntEnz: Integrated Enzyme entry for 2.4.1.130

• MetaCyc entry for 2.4.1.130

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0004584: dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase

• AMIGO entry for GO code 0004584: dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase