Disulfoglucosamine-6-sulfatase

From Wikipedia, the free encyclopedia

In enzymology, a disulfoglucosamine-6-sulfatase (EC 3.1.6.11) is an enzyme that catalyzes the chemical reaction

N,6-O-disulfo-D-glucosamine + H₂O N-sulfo-D-glucosamine + sulfate

Thus, the two substrates of this enzyme are N,6-O-disulfo-D-glucosamine and H₂O, whereas its two products are N-sulfo-D-glucosamine and sulfate.

This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name of this enzyme class is N,6-O-disulfo-D-glucosamine 6-sulfohydrolase. Other names in common use include N-sulfoglucosamine-6-sulfatase, and 6,N-disulfoglucosamine 6-O-sulfohydrolase.

[edit] References

• IUBMB entry for 3.1.6.11
• BRENDA references for 3.1.6.11 (Recommended.)
• PubMed references for 3.1.6.11
• PubMed Central references for 3.1.6.11
• Google Scholar references for 3.1.6.11
• Dietrich CP (1969). "Enzymic degradation of heparin. A sulphamidase and a sulphoesterase from Flavobacterium heparinum". Biochem. J. 111: 91–5. PMID 5775690. 

[edit] External links

The CAS registry number for this enzyme class is 37288-32-7.

• IUBMB entry for 3.1.6.11

• KEGG entry for 3.1.6.11

• BRENDA entry for 3.1.6.11

• NiceZyme view of 3.1.6.11

• EC2PDB: PDB structures for 3.1.6.11

• PRIAM entry for 3.1.6.11

• PUMA2 entry for 3.1.6.11

• IntEnz: Integrated Enzyme entry for 3.1.6.11

• MetaCyc entry for 3.1.6.11

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047871: disulfoglucosamine-6-sulfatase

• AMIGO entry for GO code 0047871: disulfoglucosamine-6-sulfatase