Discovering Dengue Drugs – Together

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Discovering Dengue Drugs – Together (DDDT) is a World Community Grid project sponsored by scientists at the University of Texas and the University of Chicago. Its goal is to identify new antiviral drugs effective against viruses from the family flaviviridae. The specific targets are:[1]

Discovering Dengue Drugs – Together will run in two phases.[2] Phase 1, launched August 21, 2007,[3] uses AutoDock 2007 (the same software used for FightAIDS@Home) to test how well antiviral drug candidates are predicted to bind to the target virus's proteases. Compounds predicted to bind strongly (protease inhibitors) are potential antiviral drug candidates.[1]

Phase 2 "will use a more computationally intensive program to screen the candidates that make it through Phase 1."[4] The drug candidates that make it through Phase 2 will then be lab-tested.[4]

[edit] References

  1. ^ a b Discovering Dengue Drugs – Together: About the Project. World Community Grid. Retrieved on 2007-08-24.
  2. ^ Didactylos (2007-06-21). Re: Project about dengue ever. World Community Grid. Retrieved on 2007-08-07.
  3. ^ Active Research. Research. World Community Grid.
  4. ^ a b lawrencehardin (2007-07-10). Re: Results.... World Community Grid. Retrieved on 2007-08-07.

[edit] External links