Discadenine synthase

From Wikipedia, the free encyclopedia

In enzymology, a discadenine synthase (EC 2.5.1.24) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + N₆-(Delta₂-isopentenyl)-adenine 5'-methylthioadenosine + discadenine

Thus, the two substrates of this enzyme are S-adenosyl-L-methionine and N6-(Delta2-isopentenyl)-adenine, whereas its two products are 5'-methylthioadenosine and discadenine.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosyl-L-methionine:N6-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferase. Other names in common use include discadenine synthetase, S-adenosyl-L-methionine:6-N-(Delta2-isopentenyl)-adenine, and 3-(3-amino-3-carboxypropyl)-transferase.

[edit] References

• IUBMB entry for 2.5.1.24
• BRENDA references for 2.5.1.24 (Recommended.)
• PubMed references for 2.5.1.24
• PubMed Central references for 2.5.1.24
• Google Scholar references for 2.5.1.24
• Taya Y, Tanaka Y, Nishimura S (1978). "Cell-free biosynthesis of discadenine, a spore germination inhibitor of Dictyostelium discoideum". FEBS. Lett. 89: 326–8. doi:10.1016/0014-5793(78)80247-6. PMID 566219. 

[edit] External links

The CAS registry number for this enzyme class is 74082-52-3.

• IUBMB entry for 2.5.1.24

• KEGG entry for 2.5.1.24

• BRENDA entry for 2.5.1.24

• NiceZyme view of 2.5.1.24

• EC2PDB: PDB structures for 2.5.1.24

• PRIAM entry for 2.5.1.24

• PUMA2 entry for 2.5.1.24

• IntEnz: Integrated Enzyme entry for 2.5.1.24

• MetaCyc entry for 2.5.1.24

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047870: discadenine synthase

• AMIGO entry for GO code 0047870: discadenine synthase