Dimethylamine dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a dimethylamine dehydrogenase (EC 1.5.8.1) is an enzyme that catalyzes the chemical reaction

dimethylamine + H₂O + electron-transferring flavoprotein methylamine + formaldehyde + reduced electron-transferring flavoprotein

The 3 substrates of this enzyme are dimethylamine, H₂O, and electron-transferring flavoprotein, whereas its 3 products are methylamine, formaldehyde, and reduced electron-transferring flavoprotein.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with a flavin as acceptor. The systematic name of this enzyme class is dimethylamine:electron-transferring flavoprotein oxidoreductase. This enzyme participates in methane metabolism. It employs one cofactor, FMN.

[edit] References

• IUBMB entry for 1.5.8.1
• BRENDA references for 1.5.8.1 (Recommended.)
• PubMed references for 1.5.8.1
• PubMed Central references for 1.5.8.1
• Google Scholar references for 1.5.8.1
• Yang CC, Packman LC, Scrutton NS (1995). "The primary structure of Hyphomicrobium X dimethylamine dehydrogenase. Relationship to trimethylamine dehydrogenase and implications for substrate recognition". Eur. J. Biochem. 232: 264–71. PMID 7556160. 

[edit] External links

• IUBMB entry for 1.5.8.1

• KEGG entry for 1.5.8.1

• BRENDA entry for 1.5.8.1

• NiceZyme view of 1.5.8.1

• EC2PDB: PDB structures for 1.5.8.1

• PRIAM entry for 1.5.8.1

• PUMA2 entry for 1.5.8.1

• IntEnz: Integrated Enzyme entry for 1.5.8.1

• MetaCyc entry for 1.5.8.1

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047133: dimethylamine dehydrogenase

• AMIGO entry for GO code 0047133: dimethylamine dehydrogenase