Differential Signaling Hypothesis
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The Differential Signaling Hypothesis is one of two models that attempt to explain how humans have immunity despite such aggressive selection (positive and negative) to kill developing T cells during their maturation process. The other model is the Differential Avidity Hypothesis.
The Differential Signaling Hypothesis states that signals tranduced differ at each stage. The first stage generates one signal, and the second stage generates a different signal.
[edit] See also
- T cell
- Differential Avidity Hypothesis - Another model to explain survival of T cells despite selection.
