Dichloromuconate cycloisomerase

From Wikipedia, the free encyclopedia

In enzymology, a dichloromuconate cycloisomerase (EC 5.5.1.11) is an enzyme that catalyzes the chemical reaction

2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate 2,4-dichloro-cis,cis-muconate

Hence, this enzyme has one substrate, 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate, and one product, 2,4-dichloro-cis,cis-muconate.

This enzyme belongs to the family of isomerases, specifically the class of intramolecular lyases. The systematic name of this enzyme class is 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing). This enzyme participates in 1,4-dichlorobenzene degradation. It employs one cofactor, manganese.

[edit] References

• IUBMB entry for 5.5.1.11
• BRENDA references for 5.5.1.11 (Recommended.)
• PubMed references for 5.5.1.11
• PubMed Central references for 5.5.1.11
• Google Scholar references for 5.5.1.11
• Kuhm AE, Schlomann M, Knackmuss HJ, Pieper DH (1990). "Purification and characterization of dichloromuconate cycloisomerase from Alcaligenes eutrophus JMP 134". Biochem. J. 266: 877–83. PMID 2327971. 

[edit] External links

The CAS registry number for this enzyme class is 126904-95-8.

• IUBMB entry for 5.5.1.11

• KEGG entry for 5.5.1.11

• BRENDA entry for 5.5.1.11

• NiceZyme view of 5.5.1.11

• EC2PDB: PDB structures for 5.5.1.11

• PRIAM entry for 5.5.1.11

• PUMA2 entry for 5.5.1.11

• IntEnz: Integrated Enzyme entry for 5.5.1.11

• MetaCyc entry for 5.5.1.11

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018852: dichloromuconate cycloisomerase

• AMIGO entry for GO code 0018852: dichloromuconate cycloisomerase