Dibenzothiophene dihydrodiol dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a dibenzothiophene dihydrodiol dehydrogenase (EC 1.3.1.60) is an enzyme that catalyzes the chemical reaction

cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD⁺ 1,2-dihydroxydibenzothiophene + NADH + H⁺

Thus, the two substrates of this enzyme are cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene and NAD⁺, whereas its 3 products are 1,2-dihydroxydibenzothiophene, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene:NAD+ oxidoreductase.

[edit] References

• IUBMB entry for 1.3.1.60
• BRENDA references for 1.3.1.60 (Recommended.)
• PubMed references for 1.3.1.60
• PubMed Central references for 1.3.1.60
• Google Scholar references for 1.3.1.60
• Laborde AL, Gibson DT (1977). "Metabolism of dibenzothiophene by a Beijerinckia species". Appl. Environ. Microbiol. 34: 783–90. PMID 596875. 
• Denome SA, Stanley DC, Olson ES, Young KD (1993). "Metabolism of dibenzothiophene and naphthalene in Pseudomonas strains: complete DNA sequence of an upper naphthalene catabolic pathway". J. Bacteriol. 175: 6890–901. PMID 8226631. 

[edit] External links

• IUBMB entry for 1.3.1.60

• KEGG entry for 1.3.1.60

• BRENDA entry for 1.3.1.60

• NiceZyme view of 1.3.1.60

• EC2PDB: PDB structures for 1.3.1.60

• PRIAM entry for 1.3.1.60

• PUMA2 entry for 1.3.1.60

• IntEnz: Integrated Enzyme entry for 1.3.1.60

• MetaCyc entry for 1.3.1.60

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018513: dibenzothiophene dihydrodiol dehydrogenase

• AMIGO entry for GO code 0018513: dibenzothiophene dihydrodiol dehydrogenase