Talk:Diabetes insipidus

From Wikipedia, the free encyclopedia

WikiProject Medicine This article is within the scope of WikiProject Medicine. Please visit the project page for details or ask questions at the doctor's mess.
B This page has been rated as B-Class on the quality assessment scale
Mid This article has been rated as Mid-importance on the importance assessment scale

Much original text for this article was taken from the public domain document "Diabetes Insipidus", NIH Publication No. 01-4620, December 2000, which states: "This e-text is not copyrighted. The clearinghouse encourages users of this e-pub to duplicate and distribute as many copies as desired."

This is a really good article, and in my opinion more articles should follow this example.18:26, 23 April 2006 (UTC)

Contents

[edit] Desmopressing/dDAVP in dipsogenic DI/primary polydipsia

Walsh's handbook of clinical endocrinology states that small doses of dDAVP may be useful in primary polydipsia. However, this requires close monitoring Oliver Keenan 18:21, 30 January 2006 (UTC)

You aren't kidding close monitoring. I have taken care of one patient in the ICU due to hyponatremic seizures because someone treated polyuria as DI without a water deprivation test. It only took 2 doses. alteripse 02:50, 31 January 2006 (UTC)

[edit] and a survivor

[1]diagnosed around 16 months but first sick around 10 months old, in 2006 going for 3 years old now and happy/healthy. Another documented case of a tuberculoma causing CDI.--Smkolins 02:32, 12 October 2006 (UTC)

[edit] treatment

why does nephrogenic DI benefit from use of a diuretic?? rhetoric 14:57, 21 October 2007 (UTC)

i answered my own question if anyone wants to make an addition:

"Hydrochlorothiazide may improve symptoms. This may be used alone or in combination with other medications, including indomethacin. Although this medication is a diuretic (these medications are usually used to increase urine output), in certain cases hydrochlorothiazide can actually reduce urine output for people with nephrogenic DI. This medication works by causing sodium and water to be excreted in the early part of the renal tubules (the proximal tubules). This leaves less fluid available for the late portion of the kidney (distal tubule) to excrete -- this is the portion affected by nephrogenic DI -- and thus it limits the total volume of urine that can be excreted."

http://www.nlm.nih.gov/medlineplus/ency/article/000511.htm rhetoric 00:42, 22 October 2007 (UTC)

[edit] Does DI have types?

"DI is caused by a deficiency of antidiuretic hormone (ADH), also known as vasopressin, due to the destruction of the back or 'posterior' part of the pituitary gland where vasopressin is normally released from, or by an insensitivity of the kidneys to that hormone."

So let me get this straight: Autoimmune destruction of the pancreas causes type 1 DM, and insulin resistance causes type 2 DM. Likewise, destruction of the posterior pituitary causes central DI, and vasopressin resistance causes nephrogenic DI. Has any reliable source called central DI "type 1" and nephrogenic DI "type 2", drawing an analogy between vasopressin in DI and insulin in DM? --Damian Yerrick (talk | stalk) 21:41, 12 May 2008 (UTC)

Every time I read information on nephrogenic cases the description was the kidney was damaged, not developing resistance.--Smkolins (talk) 06:26, 18 May 2008 (UTC)