Diatrizoic acid
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| Diatrizoic acid | |
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| IUPAC name | 3,5-diacetamido-2,4,6-triiodo-benzoic acid |
| CAS number | [737-31-5] |
| Identifiers | |
| CAS number | |
| SMILES | CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)NC(=O)C)I |
| Properties | |
| Molecular formula | C11H9I3N2O4 |
| Molar mass | 613.9 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Diatrizoic acid (or its anionic form, Diatrizoate), also known as amidotrizoic acid, or 3,5-Diacetamido-2,4,6-triiodobenzoic acid, is an iodine-containing radiocontrast agent. It is also used to kill tapeworms.
Diatrizoate is considered a high-osmolality contrast agent. Its osmolality ranges from approximately 1500 mOsm/kg (50% solution)[1] to over 2000 mOsm/kg (76% solution).[2]
[edit] Administration
- It is given intravenously (under brand name Hypaque®, GE Healthcare) to enhance contrast in computed tomography, to image the kidneys and related structures, and to image blood vessels.
- It is given orally or by enema (Gastrografin®, Gastrovist®, Gastrovision®, MD-Gastroview®) to image the gastrointestinal tract.
- It is given by Foley catheter (Cystografin®) to image the urinary tract
[edit] Contraindications
A history of sensitivity to iodine is not a contraindication to using diatrizoate, although it suggests caution in use of the agent.
[edit] References
- ^ Amersham Health (April 2006). Hypaque sodium (Diatrizoate Sodium) injection, solution. Product label. DailyMed. U.S. National Library of Medicine. Retrieved on 2007-03-29.
- ^ Amersham Health (April 2006). Hypaque (Diatrizoate Meglumine and Diatrizoate Sodium) injection, solution. Product label. DailyMed. U.S. National Library of Medicine. Retrieved on 2007-03-29.
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