Diaminopropionate ammonia-lyase

From Wikipedia, the free encyclopedia

In enzymology, a diaminopropionate ammonia-lyase (EC 4.3.1.15) is an enzyme that catalyzes the chemical reaction

2,3-diaminopropanoate + H₂O pyruvate + 2 NH₃

Thus, the two substrates of this enzyme are 2,3-diaminopropanoate and H₂O, whereas its two products are pyruvate and NH₃.

This enzyme belongs to the family of lyases, specifically ammonia lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is 2,3-diaminopropanoate ammonia-lyase (adding H2O; pyruvate-forming). Other names in common use include diaminopropionatase, alpha,beta-diaminopropionate ammonia-lyase, 2,3-diaminopropionate ammonia-lyase, and 2,3-diaminopropanoate ammonia-lyase. It employs one cofactor, pyridoxal phosphate.

[edit] References

• IUBMB entry for 4.3.1.15
• BRENDA references for 4.3.1.15 (Recommended.)
• PubMed references for 4.3.1.15
• PubMed Central references for 4.3.1.15
• Google Scholar references for 4.3.1.15
• Nagasawa T, Tanizawa K, Satoda T, Yamada H (1988). "Diaminopropionate ammonia-lyase from Salmonella typhimurium Purification and characterization of the crystalline enzyme, and sequence determination of the pyridoxal 5'-phosphate binding peptide". J. Biol. Chem. 263: 958–64. PMID 3275662. 

[edit] External links

The CAS registry number for this enzyme class is 51901-19-0.

• IUBMB entry for 4.3.1.15

• KEGG entry for 4.3.1.15

• BRENDA entry for 4.3.1.15

• NiceZyme view of 4.3.1.15

• EC2PDB: PDB structures for 4.3.1.15

• PRIAM entry for 4.3.1.15

• PUMA2 entry for 4.3.1.15

• IntEnz: Integrated Enzyme entry for 4.3.1.15

• MetaCyc entry for 4.3.1.15

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008838: diaminopropionate ammonia-lyase

• AMIGO entry for GO code 0008838: diaminopropionate ammonia-lyase