Diamine transaminase

From Wikipedia, the free encyclopedia

In enzymology, a diamine transaminase (EC 2.6.1.29) is an enzyme that catalyzes the chemical reaction

an alpha,omega-diamine + 2-oxoglutarate an omega-aminoaldehyde + L-glutamate

Thus, the two substrates of this enzyme are alpha,omega-diamine and 2-oxoglutarate, whereas its two products are omega-aminoaldehyde and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is diamine:2-oxoglutarate aminotransferase. Other names in common use include amine transaminase, amine-ketoacid transaminase, diamine aminotransferase, and diamine-ketoglutaric transaminase. This enzyme participates in urea cycle and metabolism of amino groups.

[edit] References

• IUBMB entry for 2.6.1.29
• BRENDA references for 2.6.1.29 (Recommended.)
• PubMed references for 2.6.1.29
• PubMed Central references for 2.6.1.29
• Google Scholar references for 2.6.1.29
• Kim K (1964). "Purification and properties of a diamine alpha-ketoglutarate transaminase from Escherichia coli". J. Biol. Chem. 239: 783–786. 

[edit] External links

The CAS registry number for this enzyme class is 9031-83-8.

• IUBMB entry for 2.6.1.29

• KEGG entry for 2.6.1.29

• BRENDA entry for 2.6.1.29

• NiceZyme view of 2.6.1.29

• EC2PDB: PDB structures for 2.6.1.29

• PRIAM entry for 2.6.1.29

• PUMA2 entry for 2.6.1.29

• IntEnz: Integrated Enzyme entry for 2.6.1.29

• MetaCyc entry for 2.6.1.29

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0019161: diamine transaminase

• AMIGO entry for GO code 0019161: diamine transaminase