DHRS2

From Wikipedia, the free encyclopedia

Dehydrogenase/reductase (SDR family) member 2

Identifiers

External IDs

Gene ontology
Molecular Function:	• alcohol dehydrogenase activity • oxidoreductase activity
Cellular Component:	• nucleus
Biological Process:	• electron transport • metabolic process • C21-steroid hormone metabolic process • negative regulation of progression through cell cycle

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

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Refseq

NM_005794 (mRNA)
NP_005785 (protein)

n/a (mRNA)
n/a (protein)

Location

Chr 14: 23.18 - 23.18 Mb

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Pubmed search

[1]

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Dehydrogenase/reductase (SDR family) member 2, also known as DHRS2, is a human gene.^[1]

[edit] References

^ Entrez Gene: DHRS2 dehydrogenase/reductase (SDR family) member 2.

[edit] Further reading

Donadel G, Garzelli C, Frank R, Gabrielli F (1991). "Identification of a novel nuclear protein synthesized in growth-arrested human hepatoblastoma HepG2 cells.". Eur. J. Biochem. 195 (3): 723–9. PMID 1847869.
Gabrielli F, Donadel G, Bensi G, et al. (1995). "A nuclear protein, synthesized in growth-arrested human hepatoblastoma cells, is a novel member of the short-chain alcohol dehydrogenase family.". Eur. J. Biochem. 232 (2): 473–7. PMID 7556196.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Heinz S, Krause SW, Gabrielli F, et al. (2002). "Genomic organization of the human gene HEP27: alternative promoter usage in HepG2 cells and monocyte-derived dendritic cells.". Genomics 79 (4): 608–15. doi:10.1006/geno.2002.6743. PMID 11944995.
Pellegrini S, Censini S, Guidotti S, et al. (2002). "A human short-chain dehydrogenase/reductase gene: structure, chromosomal localization, tissue expression and subcellular localization of its product.". Biochim. Biophys. Acta 1574 (3): 215–22. PMID 11997086.
Bauer K, Zemlin M, Hummel M, et al. (2002). "Diversification of Ig heavy chain genes in human preterm neonates prematurely exposed to environmental antigens.". J. Immunol. 169 (3): 1349–56. PMID 12133958.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Shafqat N, Shafqat J, Eissner G, et al. (2006). "Hep27, a member of the short-chain dehydrogenase/reductase family, is an NADPH-dependent dicarbonyl reductase expressed in vascular endothelial tissue.". Cell. Mol. Life Sci. 63 (10): 1205–13. doi:10.1007/s00018-006-6013-y. PMID 16685466.