Talk:Desloratadine

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Although its article does not include dosage information, Desloratadine itself is quite versatile. It does not cause drowsiness (mechanism of action) and it does cause drowsiness (side effects). The principle underlying this action should be documented and applied more widely. If the principle can be sufficiently generalized to be applied to things other than drugs, the possibilities are endless. One could spend money today and still have it to spend it tomorrow. One could be married and single. One could be here and there. More research is needed. Quickly. Jm546 15:25, 28 January 2006 (UTC)

I was just going to point out this contradiction, but you did it so much better than I ever could have. Now if only I knew enough to fix it. 76.202.57.153 02:33, 16 May 2007 (UTC)

Actually there is evidence that fexofenadine is more effective than desloratadine at least for preventing wheal and flare reactions caused by histamine injections so i would like to debate the notion which mentions desloratadine is evenly effective as fexofenadine.

Meltzer et al.: Efficacy of fexofenadine versus desloratadine in suppressing histamine-induced wheal and flare. Allergy Asthma Proc. 2007 Jan-Feb;28(1):67-73.

[edit] Is this a different drug

The pharamacists I've spoken with say this drug Clarinx is is nothing more than Claritan. But the body breaks this drug down to make Claritan. It is simply a way for the drug company to make more money as you have to prescribe this —Preceding unsigned comment added by 4.142.123.247 (talk) 14:54, 9 March 2008 (UTC)

I assume you’re referring to Clarinex (desloratadine) and Claritin (loratadine). Desloratadine is a metabolite of loratadine (Claritin). They’re virtually the same, so there’s no particular reason to take one rather than the other – except when you consider cost. If you’re faced with a choice between loratadine and desloratadine, and your insurance co-pay for desloratadine (currently still prescription-only) is less than the price for over-the-counter loratadine (as is generally the case), you’re obviously better off with desloratadine.
However, if you’re looking for the least-drowsy antihistamine, I’ve heard that fexofenadine (Allegra) is the best. I’ll be trying it myself soon as a replacement for cetirizine (Zyrtec), which I think has been been making me drowsy.
Disclaimer: I’m not a doctor, so you should take what I say with a grain of salt – your doctor is always the best source of medical information.
BTW: The article discussion pages here at Wikipedia are for discussing the articles themselves – not the topics they pertain to. Please use Yahoo! Answers or a similar site next time (see Wikipedia:Talk page guidelines).
Regards,
Wulf (talk) 03:44, 14 March 2008 (UTC)