Desmoglein

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The desmogleins are a family of cadherins consisting of proteins DSG1, DSG2, DSG3, and DSG4. They play a role in the formation of desmosomes that join cells to one another.

[edit] Pathology

Desmogleins are targeted in the autoimmune disease pemphigus.

[edit] External links

Histology at BU 20502loa
MeSH Desmogleins

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v • d • e Membrane proteins: cell adhesion molecules

IgSF	N-CAM (Myelin protein zero) - ICAM (1, 4) - VCAM-1 - PE-CAM - L1-CAM

Cadherins	Desmoglein - T-cadherin - protocadherin

Selectins	E-selectin - L-selectin - P-selectin

Integrins	LFA-1 - Integrin alphaXbeta2 - Macrophage-1 antigen - VLA-4 - Glycoprotein IIb/IIIa (Note: integrins not always classified as CAMs)

Other	Carcinoembryonic antigen - CD22 - CD24 - CD44 - CD146 - CD164