Deoxycytidine deaminase

From Wikipedia, the free encyclopedia

In enzymology, a deoxycytidine deaminase (EC 3.5.4.14) is an enzyme that catalyzes the chemical reaction

deoxycytidine + H₂O deoxyuridine + NH₃

Thus, the two substrates of this enzyme are deoxycytidine and H₂O, whereas its two products are deoxyuridine and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is deoxycytidine aminohydrolase. This enzyme participates in pyrimidine metabolism.

[edit] References

• IUBMB entry for 3.5.4.14
• BRENDA references for 3.5.4.14 (Recommended.)
• PubMed references for 3.5.4.14
• PubMed Central references for 3.5.4.14
• Google Scholar references for 3.5.4.14
• Cohen SS (1953). "Studies on controlling mechanisms in the metabolism of virus-infected bacteria". Cold Spring Harbour Symp. Quant. Biol. 18: 221–235. 

[edit] External links

The CAS registry number for this enzyme class is 37259-56-6.

• IUBMB entry for 3.5.4.14

• KEGG entry for 3.5.4.14

• BRENDA entry for 3.5.4.14

• NiceZyme view of 3.5.4.14

• EC2PDB: PDB structures for 3.5.4.14

• PRIAM entry for 3.5.4.14

• PUMA2 entry for 3.5.4.14

• IntEnz: Integrated Enzyme entry for 3.5.4.14

• MetaCyc entry for 3.5.4.14

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047844: deoxycytidine deaminase

• AMIGO entry for GO code 0047844: deoxycytidine deaminase