Dehydro-L-gulonate decarboxylase

From Wikipedia, the free encyclopedia

In enzymology, a dehydro-L-gulonate decarboxylase (EC 4.1.1.34) is an enzyme that catalyzes the chemical reaction

3-dehydro-L-gulonate L-xylulose + CO₂

Hence, this enzyme has one substrate, 3-dehydro-L-gulonate, and two products, L-xylulose and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-dehydro-L-gulonate carboxy-lyase (L-xylulose-forming). Other names in common use include keto-L-gulonate decarboxylase, 3-keto-L-gulonate decarboxylase, and 3-dehydro-L-gulonate carboxy-lyase. This enzyme participates in pentose and glucuronate interconversions.

[edit] References

• IUBMB entry for 4.1.1.34
• BRENDA references for 4.1.1.34 (Recommended.)
• PubMed references for 4.1.1.34
• PubMed Central references for 4.1.1.34
• Google Scholar references for 4.1.1.34
• Smiley JD and Ashwell G (1961). "Purification and properties of beta-L-hydroxy acid dehydrogenase II. Isolation of beta-keto-L-gluconic acid, an intermediate in L-xylulose biosynthesis". J. Biol. Chem. 236: 357–364. 

[edit] External links

The CAS registry number for this enzyme class is 9024-67-3.

• IUBMB entry for 4.1.1.34

• KEGG entry for 4.1.1.34

• BRENDA entry for 4.1.1.34

• NiceZyme view of 4.1.1.34

• EC2PDB: PDB structures for 4.1.1.34

• PRIAM entry for 4.1.1.34

• PUMA2 entry for 4.1.1.34

• IntEnz: Integrated Enzyme entry for 4.1.1.34

• MetaCyc entry for 4.1.1.34

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047842: dehydro-L-gulonate decarboxylase

• AMIGO entry for GO code 0047842: dehydro-L-gulonate decarboxylase