DEF6

From Wikipedia, the free encyclopedia


Differentially expressed in FDCP 6 homolog (mouse)
Identifiers
Symbol(s) DEF6; IBP
External IDs OMIM: 610094 MGI: 1346328 HomoloGene: 11103
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 50619 23853
Ensembl ENSG00000023892 ENSMUSG00000002257
Refseq NM_022047 (mRNA)
NP_071330 (protein)		 NM_027185 (mRNA)
NP_081461 (protein)
Location Chr 6: 35.37 - 35.4 Mb Chr 17: 27.94 - 27.96 Mb
Pubmed search [1] [2]

Differentially expressed in FDCP 6 homolog (mouse), also known as DEF6, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: DEF6 differentially expressed in FDCP 6 homolog (mouse).

[edit] Further reading

  • Oka T, Ihara S, Fukui Y (2007). "Cooperation of DEF6 with activated Rac in regulating cell morphology.". J. Biol. Chem. 282 (3): 2011-8. doi:10.1074/jbc.M605153200. PMID 17121847. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514. 
  • Mavrakis KJ, McKinlay KJ, Jones P, Sablitzky F (2004). "DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA.". Exp. Cell Res. 294 (2): 335-44. doi:10.1016/j.yexcr.2003.12.004. PMID 15023524. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Gupta S, Fanzo JC, Hu C, et al. (2003). "T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse.". J. Biol. Chem. 278 (44): 43541-9. doi:10.1074/jbc.M308960200. PMID 12923183. 
  • Gupta S, Lee A, Hu C, et al. (2004). "Molecular cloning of IBP, a SWAP-70 homologous GEF, which is highly expressed in the immune system.". Hum. Immunol. 64 (4): 389-401. PMID 12651066. 
  • Tanaka Y, Bi K, Kitamura R, et al. (2003). "SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells.". Immunity 18 (3): 403-14. PMID 12648457. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
 This article on a gene on chromosome 6 is a stub. You can help Wikipedia by expanding it.