Decylcitrate synthase

From Wikipedia, the free encyclopedia

In enzymology, a decylcitrate synthase (EC 2.3.3.2) is an enzyme that catalyzes the chemical reaction

lauroyl-CoA + H₂O + oxaloacetate (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA

The 3 substrates of this enzyme are lauroyl-CoA, H₂O, and oxaloacetate, whereas its two products are (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate and CoA.

This enzyme belongs to the family of transferases, specifically those acyltransferases that convert acyl groups into alkyl groups on transfer. The systematic name of this enzyme class is dodecanoyl-CoA:oxaloacetate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming). Other names in common use include 2-decylcitrate synthase, (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase, and (CoA-acylating).

[edit] References

• IUBMB entry for 2.3.3.2
• BRENDA references for 2.3.3.2 (Recommended.)
• PubMed references for 2.3.3.2
• PubMed Central references for 2.3.3.2
• Google Scholar references for 2.3.3.2
• Mahlen A, Gatenbeck S (1968). "A metabolic variation in Penicillium spiculisporum Lehman. II Purification and some properties of the enzyme synthesizing (--)-decylcitric acid". Acta. Chem. Scand. 22: 2617–23. PMID 5719165. 
• Mahlen A (1971). "Properties of 2-decylcitrate synthase from Penicillium spiculisporum Lehman". Eur. J. Biochem. 22: 104–14. doi:10.1111/j.1432-1033.1971.tb01520.x. PMID 5099208. 

[edit] External links

The CAS registry number for this enzyme class is 9068-72-8.

• IUBMB entry for 2.3.3.2

• KEGG entry for 2.3.3.2

• BRENDA entry for 2.3.3.2

• NiceZyme view of 2.3.3.2

• EC2PDB: PDB structures for 2.3.3.2

• PRIAM entry for 2.3.3.2

• PUMA2 entry for 2.3.3.2

• IntEnz: Integrated Enzyme entry for 2.3.3.2

• MetaCyc entry for 2.3.3.2

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050457: decylcitrate synthase

• AMIGO entry for GO code 0050457: decylcitrate synthase