Deacetylisoipecoside synthase

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In enzymology, a deacetylisoipecoside synthase (EC 4.3.3.3) is an enzyme that catalyzes the chemical reaction

deacetylisoipecoside + H₂O dopamine + secologanin

Thus, the two substrates of this enzyme are deacetylisoipecoside and H₂O, whereas its two products are dopamine and secologanin.

This enzyme belongs to the family of lyases, specifically amine lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is deacetylisoipecoside dopamine-lyase (secologanin-forming). This enzyme is also called deacetylisoipecoside dopamine-lyase. This enzyme participates in indole and ipecac alkaloid biosynthesis.

[edit] References

• IUBMB entry for 4.3.3.3
• BRENDA references for 4.3.3.3 (Recommended.)
• PubMed references for 4.3.3.3
• PubMed Central references for 4.3.3.3
• Google Scholar references for 4.3.3.3
• MH (1997). "Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii". Phytochemistry 45: 477–484. doi:10.1016/S0031-9422(96)00828-X. 

[edit] External links

• IUBMB entry for 4.3.3.3

• KEGG entry for 4.3.3.3

• BRENDA entry for 4.3.3.3

• NiceZyme view of 4.3.3.3

• EC2PDB: PDB structures for 4.3.3.3

• PRIAM entry for 4.3.3.3

• PUMA2 entry for 4.3.3.3

• IntEnz: Integrated Enzyme entry for 4.3.3.3

• MetaCyc entry for 4.3.3.3

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050556: deacetylisoipecoside synthase

• AMIGO entry for GO code 0050556: deacetylisoipecoside synthase