DDX42

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DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
Identifiers
Symbol(s) DDX42; FLJ43179; RHELP; RNAHP; SF3b125
External IDs MGI: 1919297 HomoloGene: 49137
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 11325 72047
Ensembl ENSG00000198231 ENSMUSG00000020705
Refseq NM_007372 (mRNA)
NP_031398 (protein)		 NM_028074 (mRNA)
NP_082350 (protein)
Location Chr 17: 59.21 - 59.25 Mb Chr 11: 106.03 - 106.07 Mb
Pubmed search [1] [2]

DEAD (Asp-Glu-Ala-Asp) box polypeptide 42, also known as DDX42, is a human gene.[1]

This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene.[1]

[edit] References

  1. ^ a b Entrez Gene: DDX42 DEAD (Asp-Glu-Ala-Asp) box polypeptide 42.

[edit] Further reading

  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
  • Uhlmann-Schiffler H, Jalal C, Stahl H (2006). "Ddx42p--a human DEAD box protein with RNA chaperone activities.". Nucleic Acids Res. 34 (1): 10–22. doi:10.1093/nar/gkj403. PMID 16397294. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain.". Mol. Cell Proteomics 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Will CL, Urlaub H, Achsel T, et al. (2002). "Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein.". EMBO J. 21 (18): 4978–88. PMID 12234937. 
  • Suk K, Kim S, Kim YH, et al. (2000). "Identification of a novel human member of the DEAD box protein family.". Biochim. Biophys. Acta 1501 (1): 63–9. PMID 10727850. 
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