DCBLD2

From Wikipedia, the free encyclopedia

Discoidin, CUB and LCCL domain containing 2

Identifiers

DCBLD2; CLCP1; ESDN

External IDs

OMIM: 608698 MGI: 1920629 HomoloGene: 12499

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• integral to plasma membrane • cell surface • membrane
Biological Process:	• cell adhesion • negative regulation of cell growth • intracellular receptor-mediated signaling pathway • wound healing

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_080927 (mRNA)
NP_563615 (protein)

NM_028523 (mRNA)
NP_082799 (protein)

Location

Chr 3: 100 - 100.1 Mb

Chr 16: 58.35 - 58.41 Mb

Pubmed search

[1]

[2]

Discoidin, CUB and LCCL domain containing 2, also known as DCBLD2, is a human gene.^[1]

[edit] References

^ Entrez Gene: DCBLD2 discoidin, CUB and LCCL domain containing 2.

[edit] Further reading

Sadeghi MM, Esmailzadeh L, Zhang J, et al. (2007). "ESDN is a marker of vascular remodeling and regulator of cell proliferation in graft arteriosclerosis.". Am. J. Transplant. 7 (9): 2098-105. doi:10.1111/j.1600-6143.2007.01919.x. PMID 17697260.
Chen Y, Low TY, Choong LY, et al. (2007). "Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells.". Proteomics 7 (14): 2384-97. doi:10.1002/pmic.200600968. PMID 17570516.
Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.". Mol. Cell Proteomics 4 (9): 1240-50. doi:10.1074/mcp.M500089-MCP200. PMID 15951569.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Koshikawa K, Osada H, Kozaki K, et al. (2002). "Significant up-regulation of a novel gene, CLCP1, in a highly metastatic lung cancer subline as well as in lung cancers in vivo.". Oncogene 21 (18): 2822-8. doi:10.1038/sj.onc.1205405. PMID 11973641.
Kobuke K, Furukawa Y, Sugai M, et al. (2001). "ESDN, a novel neuropilin-like membrane protein cloned from vascular cells with the longest secretory signal sequence among eukaryotes, is up-regulated after vascular injury.". J. Biol. Chem. 276 (36): 34105-14. doi:10.1074/jbc.M105293200. PMID 11447234.
Nadadur SS, Ehrke MJ, Gurtoo HL (2000). "A novel TNF-inducible message with putative growth suppressor function.". Biochim. Biophys. Acta 1489 (2-3): 433-9. PMID 10673047.