D-sorbitol dehydrogenase (acceptor)

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In enzymology, a D-sorbitol dehydrogenase (acceptor) (EC 1.1.99.21) is an enzyme that catalyzes the chemical reaction

D-sorbitol + acceptor L-sorbose + reduced acceptor

Thus, the two substrates of this enzyme are D-sorbitol and acceptor, whereas its two products are L-sorbose and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is D-sorbitol:acceptor 1-oxidoreductase. This enzyme is also called D-sorbitol:(acceptor) 1-oxidoreductase. This enzyme participates in fructose and mannose metabolism. It employs one cofactor, FAD.

[edit] References

• IUBMB entry for 1.1.99.21
• BRENDA references for 1.1.99.21 (Recommended.)
• PubMed references for 1.1.99.21
• PubMed Central references for 1.1.99.21
• Google Scholar references for 1.1.99.21
• Shinagawa E and Ameyama M (1982). "Purification and characterization of D-sorbitol dehydrogenase from membrane of Gluconobacter suboxydans var-alpha". Agric. Biol. Chem. 46: 135–141. 

[edit] External links

The CAS registry number for this enzyme class is 9028-22-2.

• IUBMB entry for 1.1.99.21

• KEGG entry for 1.1.99.21

• BRENDA entry for 1.1.99.21

• NiceZyme view of 1.1.99.21

• EC2PDB: PDB structures for 1.1.99.21

• PRIAM entry for 1.1.99.21

• PUMA2 entry for 1.1.99.21

• IntEnz: Integrated Enzyme entry for 1.1.99.21

• MetaCyc entry for 1.1.99.21

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047833: D-sorbitol dehydrogenase (acceptor)

• AMIGO entry for GO code 0047833: D-sorbitol dehydrogenase (acceptor)