D-ornithine 4,5-aminomutase

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In enzymology, a D-ornithine 4,5-aminomutase (EC 5.4.3.5) is an enzyme that catalyzes the chemical reaction

D-ornithine (2R,4S)-2,4-diaminopentanoate

Hence, this enzyme has one substrate, D-ornithine, and one product, (2R,4S)-2,4-diaminopentanoate.

This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring amino groups. The systematic name of this enzyme class is D-ornithine 4,5-aminomutase. Other names in common use include D-alpha-ornithine 5,4-aminomutase, and D-ornithine aminomutase. This enzyme participates in d-arginine and d-ornithine metabolism. It has 3 cofactors: pyridoxal phosphate, Cobamide coenzyme, and Dithiothreitol.

[edit] References

• IUBMB entry for 5.4.3.5
• BRENDA references for 5.4.3.5 (Recommended.)
• PubMed references for 5.4.3.5
• PubMed Central references for 5.4.3.5
• Google Scholar references for 5.4.3.5
• Somack R, Costilow RN (1973). "Purification and properties of a pyridoxal phosphate and coenzyme B 12 dependent D- -ornithine 5,4-aminomutase". Biochemistry. 12: 2597–604. doi:10.1021/bi00738a008. PMID 4711468. 

[edit] External links

The CAS registry number for this enzyme class is 62213-30-3.

• IUBMB entry for 5.4.3.5

• KEGG entry for 5.4.3.5

• BRENDA entry for 5.4.3.5

• NiceZyme view of 5.4.3.5

• EC2PDB: PDB structures for 5.4.3.5

• PRIAM entry for 5.4.3.5

• PUMA2 entry for 5.4.3.5

• IntEnz: Integrated Enzyme entry for 5.4.3.5

• MetaCyc entry for 5.4.3.5

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047831: D-ornithine 4,5-aminomutase

• AMIGO entry for GO code 0047831: D-ornithine 4,5-aminomutase