D-glutamate cyclase

From Wikipedia, the free encyclopedia

In enzymology, a D-glutamate cyclase (EC 4.2.1.48) is an enzyme that catalyzes the chemical reaction

D-glutamate 5-oxo-D-proline + H₂O

Hence, this enzyme has one substrate, D-glutamate, and two products, 5-oxo-D-proline and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming). This enzyme is also called D-glutamate hydro-lyase (cyclizing). This enzyme participates in d-glutamine and d-glutamate metabolism.

[edit] References

• IUBMB entry for 4.2.1.48
• BRENDA references for 4.2.1.48 (Recommended.)
• PubMed references for 4.2.1.48
• PubMed Central references for 4.2.1.48
• Google Scholar references for 4.2.1.48
• MEISTER A, BUKENBERGER MW, STRASSBURGER M (1963). "THE OPTICALLY-SPECIFIC ENZYMATIC CYCLIZATION OF D-GLUTAMATE". Biochem. Z. 338: 217–29. PMID 14087295. 

[edit] External links

The CAS registry number for this enzyme class is 37290-80-5.

• IUBMB entry for 4.2.1.48

• KEGG entry for 4.2.1.48

• BRENDA entry for 4.2.1.48

• NiceZyme view of 4.2.1.48

• EC2PDB: PDB structures for 4.2.1.48

• PRIAM entry for 4.2.1.48

• PUMA2 entry for 4.2.1.48

• IntEnz: Integrated Enzyme entry for 4.2.1.48

• MetaCyc entry for 4.2.1.48

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047820: D-glutamate cyclase

• AMIGO entry for GO code 0047820: D-glutamate cyclase