D-aspartate oxidase

From Wikipedia, the free encyclopedia

In enzymology, a D-aspartate oxidase (EC 1.4.3.1) is an enzyme that catalyzes the chemical reaction

D-aspartate + H₂O + O₂ oxaloacetate + NH₃ + H₂O₂

The 3 substrates of this enzyme are D-aspartate, H₂O, and O₂, whereas its 3 products are oxaloacetate, NH₃, and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with oxygen as acceptor. The systematic name of this enzyme class is D-aspartate:oxygen oxidoreductase (deaminating). Other names in common use include aspartic oxidase, and D-aspartic oxidase. This enzyme participates in alanine and aspartate metabolism. It employs one cofactor, FAD.

[edit] References

• IUBMB entry for 1.4.3.1
• BRENDA references for 1.4.3.1 (Recommended.)
• PubMed references for 1.4.3.1
• PubMed Central references for 1.4.3.1
• Google Scholar references for 1.4.3.1
• Dixon M, Kenworthy P (1967). "D-aspartate oxidase of kidney". Biochim. Biophys. Acta. 146: 54–76. PMID 6060479. 
• Still JL, Buell MV, Knox WE and Green DE (1949). "Studies on the cyclophorase system. VII. D-Aspartic oxidase". J. Biol. Chem. 179: 831–837. 
• Still JL and Sperling E (1950). "On the prosthetic group of the D-aspartic oxidase". J. Biol. Chem. 182: 585–589. 

[edit] External links

The CAS registry number for this enzyme class is 9029-20-3.

• IUBMB entry for 1.4.3.1

• KEGG entry for 1.4.3.1

• BRENDA entry for 1.4.3.1

• NiceZyme view of 1.4.3.1

• EC2PDB: PDB structures for 1.4.3.1

• PRIAM entry for 1.4.3.1

• PUMA2 entry for 1.4.3.1

• IntEnz: Integrated Enzyme entry for 1.4.3.1

• MetaCyc entry for 1.4.3.1

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008445: D-aspartate oxidase

• AMIGO entry for GO code 0008445: D-aspartate oxidase