D-arabinose 1-dehydrogenase (NAD(P)+)

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In enzymology, a D-arabinose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.117) is an enzyme that catalyzes the chemical reaction

D-arabinose + NAD(P)+ $\rightleftharpoons$ D-arabinono-1,4-lactone + NAD(P)H + H⁺

The 3 substrates of this enzyme are D-arabinose, NAD⁺, and NADP⁺, whereas its 4 products are D-arabinono-1,4-lactone, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-arabinose:NAD(P)+ 1-oxidoreductase. This enzyme is also called D-arabinose 1-dehydrogenase [NAD(P)+].

1 Structural studies
2 References
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2H6E.

[edit] References

IUBMB entry for 1.1.1.117
BRENDA references for 1.1.1.117 (Recommended.)
PubMed references for 1.1.1.117
PubMed Central references for 1.1.1.117
Google Scholar references for 1.1.1.117
Cline AL, Hu AS (1965). "The isolation of three sugar dehydrogenases from a psuedomonad". J. Biol. Chem. 240: 4488–92. PMID 5845847.
Cline AL, Hu AS (1965). "Enzymatic characterization and comparison of three sugar dehydrogenases from a pseudomonad". J. Biol. Chem. 240: 4493–7. PMID 5845848.
Cline AL, Hu AS (1965). "Some physical properties of three sugar dehydrogenases from a pseudomonad". J. Biol. Chem. 240: 4498–502. PMID 5845849.