D-arabinitol 4-dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a D-arabinitol 4-dehydrogenase (EC 1.1.1.11) is an enzyme that catalyzes the chemical reaction

D-arabinitol + NAD⁺ D-xylulose + NADH + H⁺

Thus, the two substrates of this enzyme are D-arabinitol and NAD⁺, whereas its 3 products are D-xylulose, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-arabinitol:NAD+ 4-oxidoreductase. Other names in common use include D-arabitol dehydrogenase, and arabitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism.

[edit] References

• IUBMB entry for 1.1.1.11
• BRENDA references for 1.1.1.11 (Recommended.)
• PubMed references for 1.1.1.11
• PubMed Central references for 1.1.1.11
• Google Scholar references for 1.1.1.11
• Lin ECC (1961). "An inducible D-arabitol dehydrogenase from Aerobacter aerogenes". J. Biol. Chem. 236: 31–36. 
• Wood WA, McDonough MJ and Jacobs LB (1961). "Ribitol and D-arabitol utilization by Aerobacter aerogenes". J. Biol. Chem. 236: 2190–2195. 

[edit] External links

The CAS registry number for this enzyme class is 9028-18-6.

• IUBMB entry for 1.1.1.11

• KEGG entry for 1.1.1.11

• BRENDA entry for 1.1.1.11

• NiceZyme view of 1.1.1.11

• EC2PDB: PDB structures for 1.1.1.11

• PRIAM entry for 1.1.1.11

• PUMA2 entry for 1.1.1.11

• IntEnz: Integrated Enzyme entry for 1.1.1.11

• MetaCyc entry for 1.1.1.11

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047813: D-arabinitol 4-dehydrogenase

• AMIGO entry for GO code 0047813: D-arabinitol 4-dehydrogenase