D-arabinitol 2-dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a D-arabinitol 2-dehydrogenase (EC 1.1.1.250) is an enzyme that catalyzes the chemical reaction

D-arabinitol + NAD⁺ D-ribulose + NADH + H⁺

Thus, the two substrates of this enzyme are D-arabinitol and NAD⁺, whereas its 3 products are D-ribulose, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-arabinitol:NAD+ 2-oxidoreductase (D-ribulose-forming). This enzyme is also called D-arabinitol 2-dehydrogenase (ribulose-forming).

[edit] References

• IUBMB entry for 1.1.1.250
• BRENDA references for 1.1.1.250 (Recommended.)
• PubMed references for 1.1.1.250
• PubMed Central references for 1.1.1.250
• Google Scholar references for 1.1.1.250
• Wong B, Murray JS, Castellanos M, Croen KD (1993). "D-arabitol metabolism in Candida albicans: studies of the biosynthetic pathway and the gene that encodes NAD-dependent D-arabitol dehydrogenase". J. Bacteriol. 175: 6314–20. PMID 8407803. 
• Quong MW, Miyada CG, Switchenko AC, Goodman TC (1993). "Identification, purification, and characterization of a D-arabinitol-specific dehydrogenase from Candida tropicalis". Biochem. Biophys. Res. Commun. 196: 1323–9. doi:10.1006/bbrc.1993.2397. PMID 8250887. 

[edit] External links

The CAS registry number for this enzyme class is 336883-93-3.

• IUBMB entry for 1.1.1.250

• KEGG entry for 1.1.1.250

• BRENDA entry for 1.1.1.250

• NiceZyme view of 1.1.1.250

• EC2PDB: PDB structures for 1.1.1.250

• PRIAM entry for 1.1.1.250

• PUMA2 entry for 1.1.1.250

• IntEnz: Integrated Enzyme entry for 1.1.1.250

• MetaCyc entry for 1.1.1.250

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047038: D-arabinitol 2-dehydrogenase

• AMIGO entry for GO code 0047038: D-arabinitol 2-dehydrogenase