Talk:Cystic fibrosis transmembrane conductance regulator
From Wikipedia, the free encyclopedia
 |
This article is part of WikiProject Genetics, an attempt to build a comprehensive and detailed guide to genetics on Wikipedia. If you would like to participate, you can edit this page, or visit the project page to join the project and/or contribute to the discussion. |
| ??? | This article has not yet received a rating on the quality scale. |
| ??? | This article has not yet received an importance rating. |
 |
This article is supported by the WikiProject on Medical Genetics, which gives a central approach to Medical genetics and related subjects on Wikipedia. Please participate by editing the article Cystic fibrosis transmembrane conductance regulator, or visit the project page for more details on the projects. |
| B | This article has been rated as B-Class on the quality scale. |
 |
This article is within the scope of the Molecular and Cellular Biology WikiProject. To participate, visit the WikiProject for more information. The WikiProject's current monthly collaboration is focused on improving Restriction enzyme. |
||
| B | This article has been rated as B-Class on the assessment scale. |
||
| Mid | This article is on a subject of Mid-importance within molecular and cellular biology. | ||
|
Article Grading: The article has been rated for quality and/or importance but has no comments yet. If appropriate, please review the article and then leave comments here to identify the strengths and weaknesses of the article and what work it will need. |
|||
The online book Genes and Disease has it right. In most tissues, transport of chloride ions by the CFTR is followed by movement of sodium ions in the same direction. --JWSchmidt 02:22, 2 October 2006 (UTC)
In the article Non-specific activation of the epithelial sodium channel by the CFTR chloride channel Nagel et al conclude, "Electrochemical coupling predicts that activation of CFTR then leads to a change in membrane potential and increased Na+ conductance, as indeed found by Reddy et al. (1999)," and also, "activated CFTR must lead.....according to the Goldmann–Hodgkin–Katz equation (Hille, 1992), to a voltage-dependent sodium conductance."
--JWSchmidt 02:59, 2 October 2006 (UTC)
- Thank you - sounds good to me. --Arcadian 03:00, 2 October 2006 (UTC)
[edit] does CFTR transport Mg as well as Cl?
Hello, an anonymous user changed the text so that it says that magnesium ions are also conveyed through cell membranes, thanks to this protein, as seen in this diff.
I've fixed the formatting of the added link, but I don't know whether or not the content is accurate. Does anybody else know? Thanks, --Kyoko 21:35, 13 April 2007 (UTC)
That is an error, only chloride ions are conveyed through cell membranes via this pathway.—Preceding unsigned comment added by 139.80.7.95 (talk • contribs)
