Cyanoalanine nitrilase

From Wikipedia, the free encyclopedia

In enzymology, a cyanoalanine nitrilase (EC 3.5.5.4) is an enzyme that catalyzes the chemical reaction

3-cyano-L-alanine + 2 H₂O L-aspartate + NH₃

Thus, the two substrates of this enzyme are 3-cyano-L-alanine and H₂O, whereas its two products are L-aspartate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in nitriles. The systematic name of this enzyme class is 3-cyano-L-alanine aminohydrolase. This enzyme is also called beta-cyanoalanine nitrilase. This enzyme participates in cyanoamino acid metabolism.

[edit] References

• IUBMB entry for 3.5.5.4
• BRENDA references for 3.5.5.4 (Recommended.)
• PubMed references for 3.5.5.4
• PubMed Central references for 3.5.5.4
• Google Scholar references for 3.5.5.4
• Yanase H, Sakai T and Tonomuro K (1983). "Purification, crystallization and some properties of beta-cyano-L-alanine-degrading enzyme in Pseudomonas sp. 13". Agric. Biol. Chem. 47: 473–482. 

[edit] External links

The CAS registry number for this enzyme class is 85638-44-4.

• IUBMB entry for 3.5.5.4

• KEGG entry for 3.5.5.4

• BRENDA entry for 3.5.5.4

• NiceZyme view of 3.5.5.4

• EC2PDB: PDB structures for 3.5.5.4

• PRIAM entry for 3.5.5.4

• PUMA2 entry for 3.5.5.4

• IntEnz: Integrated Enzyme entry for 3.5.5.4

• MetaCyc entry for 3.5.5.4

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047427: cyanoalanine nitrilase

• AMIGO entry for GO code 0047427: cyanoalanine nitrilase