Cyanide hydratase

From Wikipedia, the free encyclopedia

In enzymology, a cyanide hydratase (EC 4.2.1.66) is an enzyme that catalyzes the chemical reaction

formamide cyanide + H₂O

Hence, this enzyme has one substrate, formamide, and two products, cyanide and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is formamide hydro-lyase (cyanide-forming). Other names in common use include formamide dehydratase, and formamide hydro-lyase. This enzyme participates in cyanoamino acid metabolism.

[edit] References

• IUBMB entry for 4.2.1.66
• BRENDA references for 4.2.1.66 (Recommended.)
• PubMed references for 4.2.1.66
• PubMed Central references for 4.2.1.66
• Google Scholar references for 4.2.1.66
• Fry WE, Millar RL (1972). "Cyanide degradion by an enzyme from Stemphylium loti". Arch. Biochem. Biophys. 151: 468–74. doi:10.1016/0003-9861(72)90523-1. PMID 5065258. 

[edit] External links

The CAS registry number for this enzyme class is 37292-83-4.

• IUBMB entry for 4.2.1.66

• KEGG entry for 4.2.1.66

• BRENDA entry for 4.2.1.66

• NiceZyme view of 4.2.1.66

• EC2PDB: PDB structures for 4.2.1.66

• PRIAM entry for 4.2.1.66

• PUMA2 entry for 4.2.1.66

• IntEnz: Integrated Enzyme entry for 4.2.1.66

• MetaCyc entry for 4.2.1.66

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0030196: cyanide hydratase

• AMIGO entry for GO code 0030196: cyanide hydratase