CUZD1

From Wikipedia, the free encyclopedia

CUB and zona pellucida-like domains 1

Identifiers

CUZD1; ERG-1; UO-44

External IDs

MGI: 1202881 HomoloGene: 7389

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• membrane • integral to membrane • zymogen granule membrane
Biological Process:	• substrate-bound cell migration, cell attachment to substrate • cell cycle • cell adhesion • cell proliferation • trypsinogen activation • cell division

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_022034 (mRNA)
NP_071317 (protein)

NM_008411 (mRNA)
NP_032437 (protein)

Location

n/a

Chr 7: 131.1 - 131.11 Mb

Pubmed search

[1]

[2]

CUB and zona pellucida-like domains 1, also known as CUZD1, is a human gene.^[1]

[edit] References

^ Entrez Gene: CUZD1 CUB and zona pellucida-like domains 1.

[edit] Further reading

Leong CT, Ong CK, Tay SK, Huynh H (2007). "Silencing expression of UO-44 (CUZD1) using small interfering RNA sensitizes human ovarian cancer cells to cisplatin in vitro.". Oncogene 26 (6): 870-80. doi:10.1038/sj.onc.1209836. PMID 16862170.
Blanchetot C, Chagnon M, Dubé N, et al. (2005). "Substrate-trapping techniques in the identification of cellular PTP targets.". Methods 35 (1): 44-53. doi:10.1016/j.ymeth.2004.07.007. PMID 15588985.
Leong CT, Ng CY, Ong CK, et al. (2004). "Molecular cloning, characterization and isolation of novel spliced variants of the human ortholog of a rat estrogen-regulated membrane-associated protein, UO-44.". Oncogene 23 (33): 5707-18. doi:10.1038/sj.onc.1207754. PMID 15184879.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375-81. doi:10.1038/nature02462. PMID 15164054.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309.
Cayabyab FS, Tsui FW, Schlichter LC (2003). "Modulation of the ERG K+ current by the tyrosine phosphatase, SHP-1.". J. Biol. Chem. 277 (50): 48130-8. doi:10.1074/jbc.M208448200. PMID 12361947.
Huynh H, Ng CY, Lim KB, et al. (2001). "Induction of UO-44 gene expression by tamoxifen in the rat uterus and ovary.". Endocrinology 142 (7): 2985-95. PMID 11416020.
Chen D, Xu X, Zhu LJ, et al. (1999). "Cloning and uterus/oviduct-specific expression of a novel estrogen-regulated gene (ERG1)". J. Biol. Chem. 274 (45): 32215-24. PMID 10542259.