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| ctRNA |
 |
| Type: |
Gene; antisense; |
| 2° structure: |
Published; PubMed |
| Seed alignment: |
PubMed |
| Avg length: |
76.6 nucleotides |
| Avg identity: |
67% |
|
Rolling circle replication plasmids contain a number of mechanisms to maintain a low copy number. One of these methods is to transcribe a small RNA called ctRNA (for counter-transcribed RNA) than is transcribed on the opposite strand to RepB the replication initiation protein. ctRNA binds to the mRNA of repB and causes translational inhibition [1].
[edit] References
- ^ Venkova-Canova, T; Patek M, Nesvera J (2003). "Control of rep gene expression in plasmid pGA1 from Corynebacterium glutamicum". J Bacteriol 185: 2402–2409. doi:10.1128/JB.185.8.2402-2409.2003. PMID 12670963.
[edit] External links
