CTP synthase
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CTP synthase
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Identifiers | |
Symbol | CTPS |
Entrez | 1503 |
HUGO | 2519 |
OMIM | 123860 |
PDB | 1s1m |
RefSeq | NM_001905 |
UniProt | P17812 |
Other data | |
EC number | 6.3.4.2 |
Locus | Chr. 1 p34.1 |
CTP synthase (or CTP synthetase) is an enzyme involved in pyrimidine biosynthesis.
It intraconverts UTP and CTP. The source of the amine/amino group in CTP is glutamine.
CTP synthase is activated by GTP, a purine. This acts to balance the relative amounts of purine and pyrimidine nucleotides.
CTP synthase is inhibited by CTP.
CTP (Note nitrogen in upper right. Ignore rotation.) |
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