CTDSP1

From Wikipedia, the free encyclopedia

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1

PDB rendering based on 1t9z.

Available structures: 1t9z, 1ta0, 2ghq, 2ght

Identifiers

Symbol(s)

CTDSP1; SCP1; NLIIF

External IDs

OMIM: 605323 MGI: 2654470 HomoloGene: 48881

Gene ontology
Molecular Function:	• molecular_function • phosphoprotein phosphatase activity • hydrolase activity • phosphoric monoester hydrolase activity
Cellular Component:	• nucleus
Biological Process:	• biological_process

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_021198 (mRNA)
NP_067021 (protein)

XM_989774 (mRNA)
XP_994868 (protein)

Location

Chr 2: 218.97 - 218.98 Mb

n/a

Pubmed search

[1]

[2]

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1, also known as CTDSP1, is a human gene.^[1]

[edit] References

^ Entrez Gene: CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1.

[edit] Further reading

Marquet S, Lepage P, Hudson TJ, et al. (2000). "Complete nucleotide sequence and genomic structure of the human NRAMP1 gene region on chromosome region 2q35.". Mamm. Genome 11 (9): 755–62. PMID 10967134.
Ma X, Wright J, Dou S, et al. (2002). "Ethnic divergence and linkage disequilibrium of novel SNPs in the human NLI-IF gene: evidence of human origin and lack of association with tuberculosis susceptibility.". J. Hum. Genet. 47 (3): 140–5. PMID 11950066.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Yeo M, Lin PS, Dahmus ME, Gill GN (2003). "A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5.". J. Biol. Chem. 278 (28): 26078–85. doi:10.1074/jbc.M301791200. PMID 12721286.
Fernandes AO, Campagnoni CW, Kampf K, et al. (2004). "Identification of a protein that interacts with the golli-myelin basic protein and with nuclear LIM interactor in the nervous system.". J. Neurosci. Res. 75 (4): 461–71. doi:10.1002/jnr.10882. PMID 14743429.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Yeo M, Lee SK, Lee B, et al. (2005). "Small CTD phosphatases function in silencing neuronal gene expression.". Science 307 (5709): 596–600. doi:10.1126/science.1100801. PMID 15681389.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Sapkota G, Knockaert M, Alarcón C, et al. (2007). "Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.". J. Biol. Chem. 281 (52): 40412–9. doi:10.1074/jbc.M610172200. PMID 17085434.