CSRP1

From Wikipedia, the free encyclopedia


Cysteine and glycine-rich protein 1
PDB rendering based on 1ctl.
Available structures: 1ctl
Identifiers
Symbol(s) CSRP1; CRP1; CRP; CSRP; CYRP; D1S181E; DKFZp686M148
External IDs OMIM: 123876 MGI: 88549 HomoloGene: 37874
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 1465 13007
Ensembl ENSG00000159176 ENSMUSG00000026421
Uniprot P21291 Q4FJX4
Refseq NM_004078 (mRNA)
NP_004069 (protein)		 NM_007791 (mRNA)
NP_031817 (protein)
Location Chr 1: 199.72 - 199.75 Mb Chr 1: 137.54 - 137.57 Mb
Pubmed search [1] [2]

Cysteine and glycine-rich protein 1, also known as CSRP1, is a human gene.[1]

CSRP1 is a member of the CSRP family of genes encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in CRP1 is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation Other genes in the family include CSRP2 and CSRP3.[1]

[edit] References

  1. ^ a b Entrez Gene: CSRP1 cysteine and glycine-rich protein 1.

[edit] Further reading

  • Weiskirchen R, Günther K (2003). "The CRP/MLP/TLP family of LIM domain proteins: acting by connecting.". Bioessays 25 (2): 152–62. doi:10.1002/bies.10226. PMID 12539241. 
  • Wang X, Lee G, Liebhaber SA, Cooke NE (1992). "Human cysteine-rich protein. A member of the LIM/double-finger family displaying coordinate serum induction with c-myc.". J. Biol. Chem. 267 (13): 9176–84. PMID 1374386. 
  • Wang X, Ray K, Szpirer J, et al. (1992). "Analysis of the human cysteine-rich protein gene (CSRP), assignment to chromosome 1q24-1q32, and identification of an associated MspI polymorphism.". Genomics 14 (2): 391–7. PMID 1385304. 
  • Liebhaber SA, Emery JG, Urbanek M, et al. (1990). "Characterization of a human cDNA encoding a widely expressed and highly conserved cysteine-rich protein with an unusual zinc-finger motif.". Nucleic Acids Res. 18 (13): 3871–9. PMID 2115670. 
  • Feuerstein R, Wang X, Song D, et al. (1994). "The LIM/double zinc-finger motif functions as a protein dimerization domain.". Proc. Natl. Acad. Sci. U.S.A. 91 (22): 10655–9. PMID 7938009. 
  • Dubé JY, Chapdelaine P, Trahan PL, et al. (1998). "Abundant cysteine-rich protein-1 is localized in the stromal compartment of the human prostate.". Arch. Androl. 40 (2): 109–15. PMID 9507743. 
  • Erdel M, Weiskirchen R (1999). "Assignment1 of CSRP1 encoding the LIM domain protein CRP1, to human chromosome 1q32 by fluorescence in situ hybridization.". Cytogenet. Cell Genet. 83 (1-2): 10–1. PMID 9925910. 
  • Harper BD, Beckerle MC, Pomiès P (2001). "Fine mapping of the alpha-actinin binding site within cysteine-rich protein.". Biochem. J. 350 Pt 1: 269–74. PMID 10926853. 
  • Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus.". Curr. Biol. 12 (1): 1–11. PMID 11790298. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
  • Hirasawa Y, Arai M, Imazeki F, et al. (2007). "Methylation status of genes upregulated by demethylating agent 5-aza-2'-deoxycytidine in hepatocellular carcinoma.". Oncology 71 (1-2): 77–85. doi:10.1159/000100475. PMID 17341888. 
  • Wang Q, Williamson M, Bott S, et al. (2007). "Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer.". Oncogene 26 (45): 6560–5. doi:10.1038/sj.onc.1210472. PMID 17486081. 
 This article on a gene on chromosome 1 is a stub. You can help Wikipedia by expanding it.