CSPG5

From Wikipedia, the free encyclopedia

Chondroitin sulfate proteoglycan 5 (neuroglycan C)

Identifiers

CSPG5; MGC44034; NGC

External IDs

OMIM: 606775 MGI: 1352747 HomoloGene: 4795

Gene ontology
Molecular Function:	• protein binding • growth factor activity
Cellular Component:	• membrane fraction • Golgi apparatus • integral to plasma membrane • membrane • Golgi-associated vesicle membrane
Biological Process:	• regulation of cell growth • multicellular organismal development • nervous system development • cell differentiation • intracellular transport • regulation of synaptic transmission

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006574 (mRNA)
NP_006565 (protein)

XM_979119 (mRNA)
XP_984213 (protein)

Location

Chr 3: 47.58 - 47.6 Mb

Chr 9: 110.09 - 110.11 Mb

Pubmed search

[1]

[2]

Chondroitin sulfate proteoglycan 5 (neuroglycan C), also known as CSPG5, is a human gene.^[1]

[edit] References

^ Entrez Gene: CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C).

[edit] Further reading

Ichihara-Tanaka K, Oohira A, Rumsby M, Muramatsu T (2006). "Neuroglycan C is a novel midkine receptor involved in process elongation of oligodendroglial precursor-like cells.". J. Biol. Chem. 281 (41): 30857–64. doi:10.1074/jbc.M602228200. PMID 16901907.
Aono S, Tokita Y, Yasuda Y, et al. (2006). "Expression and identification of a new splice variant of neuroglycan C, a transmembrane chondroitin sulfate proteoglycan, in the human brain.". J. Neurosci. Res. 83 (1): 110–8. doi:10.1002/jnr.20698. PMID 16299773.
Kinugasa Y, Ishiguro H, Tokita Y, et al. (2004). "Neuroglycan C, a novel member of the neuregulin family.". Biochem. Biophys. Res. Commun. 321 (4): 1045–9. doi:10.1016/j.bbrc.2004.07.066. PMID 15358134.
Hassel B, Schreff M, Stube EM, et al. (2003). "CALEB/NGC interacts with the Golgi-associated protein PIST.". J. Biol. Chem. 278 (41): 40136–43. doi:10.1074/jbc.M305577200. PMID 12885772.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863.
Yasuda Y, Tokita Y, Aono S, et al. (1999). "Cloning and chromosomal mapping of the human gene of neuroglycan C (NGC), a neural transmembrane chondroitin sulfate proteoglycan with an EGF module.". Neurosci. Res. 32 (4): 313–22. PMID 9950058.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. PMID 8889548.