CRYZL1

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Crystallin, zeta (quinone reductase)-like 1
Identifiers
Symbol(s) CRYZL1; 4P11; QOH-1
External IDs OMIM: 603920 MGI: 1913859 HomoloGene: 3749
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 9946 66609
Ensembl ENSG00000205758 ENSMUSG00000058240
Uniprot O95825 Q921W4
Refseq NM_145858 (mRNA)
NP_665857 (protein)		 NM_133679 (mRNA)
NP_598440 (protein)
Location Chr 21: 33.88 - 33.94 Mb Chr 16: 91.58 - 91.62 Mb
Pubmed search [1] [2]

Crystallin, zeta (quinone reductase)-like 1, also known as CRYZL1, is a human gene.[1]

This gene encodes a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined.[1]

[edit] References

  1. ^ a b Entrez Gene: CRYZL1 crystallin, zeta (quinone reductase)-like 1.

[edit] Further reading

  • Mount SM (2000). "Genomic sequence, splicing, and gene annotation.". Am. J. Hum. Genet. 67 (4): 788–92. PMID 10986039. 
  • Kim MY, Lee HK, Park JS, et al. (1999). "Identification of a zeta-crystallin (quinone reductase)-like 1 gene (CRYZL1) mapped to human chromosome 21q22.1.". Genomics 57 (1): 156–9. doi:10.1006/geno.1998.5714. PMID 10191096. 
  • Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21.". Nature 405 (6784): 311–9. doi:10.1038/35012518. PMID 10830953. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560. 
  • Hu YH, Warnatz HJ, Vanhecke D, et al. (2006). "Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins.". BMC Genomics 7: 155. doi:10.1186/1471-2164-7-155. PMID 16780588. 
  • Fernández MR, Porté S, Crosas E, et al. (2007). "Human and yeast zeta-crystallins bind AU-rich elements in RNA.". Cell. Mol. Life Sci. 64 (11): 1419–27. doi:10.1007/s00018-007-7091-1. PMID 17497241. 
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