CRKRS

From Wikipedia, the free encyclopedia

Cdc2-related kinase, arginine/serine-rich

Identifiers

CRKRS; CRK7; CRKR; KIAA0904

External IDs

Gene ontology
Molecular Function:	• nucleotide binding • RNA polymerase II transcription factor activity • protein serine/threonine kinase activity • ATP binding • transferase activity
Cellular Component:	• nucleus
Biological Process:	• protein amino acid autophosphorylation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_016507 (mRNA)
NP_057591 (protein)

NM_026952 (mRNA)
NP_081228 (protein)

Location

Chr 17: 34.87 - 34.94 Mb

Chr 11: 98.02 - 98.07 Mb

Pubmed search

[1]

[2]

Cdc2-related kinase, arginine/serine-rich, also known as CRKRS, is a human gene.^[1]

[edit] References

^ Entrez Gene: CRKRS Cdc2-related kinase, arginine/serine-rich.

[edit] Further reading

Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99-106. PMID 12168954.
Wissing J, Jänsch L, Nimtz M, et al. (2007). "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.". Mol. Cell Proteomics 6 (3): 537-47. doi:10.1074/mcp.T600062-MCP200. PMID 17192257.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285-92. doi:10.1038/nbt1240. PMID 16964243.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi:10.1101/gr.4039406. PMID 16344560.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324-32. doi:10.1101/gr.2334104. PMID 15231748.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ko TK, Kelly E, Pines J (2002). "CrkRS: a novel conserved Cdc2-related protein kinase that colocalises with SC35 speckles.". J. Cell. Sci. 114 (Pt 14): 2591-603. PMID 11683387.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 5 (6): 355-64. PMID 10048485.