Cr mimetic

Caloric restriction mimetics try to mimic the substantial anti-aging effects caloric restriction has on many laboratory animals.

Candidate compounds include:

Resveratrol is found in red wine and grapes^{[citation needed]}. Many supplement companies market inexpensive concentrates.
metformin mimics the gene expression of CR mice^{[citation needed]}, and has extended mice's maximum life spans^{[citation needed]}. It is already clinically approved to treat diabetes.
Lipoic Acid (α-Lipoic Acid, Alpha Lipoic Acid, or ALA)^{[citation needed]}
2-deoxy-D-glucose, or 2-DG^[1]. 2-DG interferes in glycolysis, starving a cell of fuel.
Iodoacetate^{[citation needed]}

[edit] References

^ Schulz TJ, Zarse K, Voigt A, Urban N, Birringer M, Ristow M (2007). "Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress". Cell Metab. 6 (4): 280–93. doi:10.1016/j.cmet.2007.08.011. PMID 17908557.