CPSF3
From Wikipedia, the free encyclopedia
Cleavage and polyadenylation specific factor 3, 73kDa
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PDB rendering based on 2i7t. | ||||||||||||||
Available structures: 2i7t, 2i7v | ||||||||||||||
Identifiers | ||||||||||||||
Symbol(s) | CPSF3; CPSF; CPSF-73; CPSF73 | |||||||||||||
External IDs | OMIM: 606029 MGI: 1859328 HomoloGene: 6499 | |||||||||||||
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Orthologs | ||||||||||||||
Human | Mouse | |||||||||||||
Entrez | 51692 | 54451 | ||||||||||||
Ensembl | ENSG00000119203 | ENSMUSG00000054309 | ||||||||||||
Uniprot | Q9UKF6 | Q3TC91 | ||||||||||||
Refseq | NM_016207 (mRNA) NP_057291 (protein) |
NM_018813 (mRNA) NP_061283 (protein) |
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Location | Chr 2: 9.48 - 9.53 Mb | Chr 12: 21.53 - 21.56 Mb | ||||||||||||
Pubmed search | [1] | [2] |
Cleavage and polyadenylation specific factor 3, 73kDa, also known as CPSF3, is a human gene.[1]
[edit] References
[edit] Further reading
- Murthy KG, Manley JL (1995). "The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation.". Genes Dev. 9 (21): 2672–83. PMID 7590244.
- Jenny A, Hauri HP, Keller W (1994). "Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit.". Mol. Cell. Biol. 14 (12): 8183–90. PMID 7969155.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
- Thuresson AC, Aström J, Aström A, et al. (1994). "Multiple forms of poly(A) polymerases in human cells.". Proc. Natl. Acad. Sci. U.S.A. 91 (3): 979–83. PMID 8302877.
- Jenny A, Minvielle-Sebastia L, Preker PJ, Keller W (1996). "Sequence similarity between the 73-kilodalton protein of mammalian CPSF and a subunit of yeast polyadenylation factor I.". Science 274 (5292): 1514–7. PMID 8929409.
- McCracken S, Fong N, Yankulov K, et al. (1997). "The C-terminal domain of RNA polymerase II couples mRNA processing to transcription.". Nature 385 (6614): 357–61. doi: . PMID 9002523.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
- Takagaki Y, Manley JL (2000). "Complex protein interactions within the human polyadenylation machinery identify a novel component.". Mol. Cell. Biol. 20 (5): 1515–25. PMID 10669729.
- de Vries H, Rüegsegger U, Hübner W, et al. (2000). "Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors.". EMBO J. 19 (21): 5895–904. doi: . PMID 11060040.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: . PMID 12477932.
- Kaufmann I, Martin G, Friedlein A, et al. (2005). "Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase.". EMBO J. 23 (3): 616–26. doi: . PMID 14749727.
- Calzado MA, Sancho R, Muñoz E (2004). "Human immunodeficiency virus type 1 Tat increases the expression of cleavage and polyadenylation specificity factor 73-kilodalton subunit modulating cellular and viral expression.". J. Virol. 78 (13): 6846–54. doi: . PMID 15194760.
- Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.". Curr. Biol. 14 (16): 1436–50. doi: . PMID 15324660.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi: . PMID 15489334.
- Mandel CR, Kaneko S, Zhang H, et al. (2007). "Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.". Nature 444 (7121): 953–6. doi: . PMID 17128255.
- de la Vega L, Sánchez-Duffhues G, Fresno M, et al. (2007). "The 73 kDa subunit of the CPSF complex binds to the HIV-1 LTR promoter and functions as a negative regulatory factor that is inhibited by the HIV-1 Tat protein.". J. Mol. Biol. 372 (2): 317–30. doi: . PMID 17669424.