CPNE4

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Copine IV
Identifiers
Symbol(s) CPNE4; COPN4; CPN4; MGC15604
External IDs OMIM: 604208 MGI: 1921270 HomoloGene: 26078
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 131034 74020
Ensembl ENSG00000196353 ENSMUSG00000032564
Uniprot Q96A23 Q8BLR2
Refseq NM_130808 (mRNA)
NP_570720 (protein)		 NM_028719 (mRNA)
NP_082995 (protein)
Location Chr 3: 132.74 - 133.24 Mb Chr 9: 104.41 - 104.89 Mb
Pubmed search [1] [2]

Copine IV, also known as CPNE4, is a human gene.[1]

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus.[1]

[edit] References

  1. ^ a b Entrez Gene: CPNE4 copine IV.

[edit] Further reading

  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Maitra R, Grigoryev DN, Bera TK, et al. (2003). "Cloning, molecular characterization, and expression analysis of Copine 8.". Biochem. Biophys. Res. Commun. 303 (3): 842-7. PMID 12670487. 
  • Tomsig JL, Snyder SL, Creutz CE (2003). "Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.". J. Biol. Chem. 278 (12): 10048-54. doi:10.1074/jbc.M212632200. PMID 12522145. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Creutz CE, Tomsig JL, Snyder SL, et al. (1998). "The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans.". J. Biol. Chem. 273 (3): 1393-402. PMID 9430674. 
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