Talk:Compounding

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[edit] America

Hmm, why do some Americans have the habit of assuming there is no life beyond the borders of their country? In the regulation section it states "pharmacies follow guidelines from U.S. Pharmacopeia." This is not true. US based pharmacies may indeed follow guidelines from the USP but, outside of America it is the EP or the BP or any number of alternative Pharmacopeias which are used.

Similar logic may be applied to "Compounding pharmacists must work within the jurisdiction of the FDA, they are simply exempt from many FDA requirements so long as they are state-compliant and compound pursuant to a valid prescription. However, the FDA registers and inspects the facilities that supply manufacturers with active pharmaceutical ingredients."

I'm sure this was an honest mistake/oversight, but it is all too common on wikipedia. Dammit America - open your eyes and open your minds!

I will sort this out if I get time, if anyone else wants a go - be my guest! —The preceding unsigned comment was added by 155.137.0.9 (talk) 14:39, 15 February 2007 (UTC).

Compounded drugs may be referred to galenic or magistral formulations in other countries. The names that refer to the process of making drugs from scratch are as different as their oversight across the globe. Approximately 20 years ago, chemical repackagers in the US began to exploit the profession of pharmacy with the idea of selling chemicals and recipes to pharmacists who could make more money if they sold drugs made from scratch in lieu of approved products. They monitor drugs in development, and actually "bring them to market" before approval for safety and effectiveness. In other countries, this practice is not generally tolerated--pharmacists cannot develop and market novel remedies without submitting to drug regulatory authorities, and most drugs are required to be manufactured according to national standards. Not the case in the US? Hmmm...the new "gold standard" or "double-standard"? ---A Global American —Preceding unsigned comment added by Tara5g (talk • contribs)

All of this is pretty irrelevant to the main page, edit the main page and provide sources if this info is going to be included. WLU 13:02, 22 June 2007 (UTC)

[edit] Polypharmacy POV section removed

There might be a valid criticism here, but the prose is argumentative rather than encyclopedic, and is not up to Wikipedia standards. Here is the section removed if someone feels up to reworking it.

The neutrality of this section is disputed. Please see the discussion on the talk page.(December 2007) Please do not remove this message until the dispute is resolved.

The stance of the FDA has been that each time a drug is compounded it creates a “new drug”. Since that “new drug” has not received FDA approval, the FDA then claims the compound is adulterated and therefore illegal. The illogic of such a position is clarified when one considers the actual practice of medicine in the United States, which uses multiple medications simultaneously (polypharmacy).

While many people take two or more medications daily, very few prescription drugs are studied when combined together. This polypharmacy is impossible to study because of the difficulty and the cost of conducting a full-scale study of each drug combination. For example say there are three hundred drugs available for a doctor to choose from. If a patient is taking an average of six prescription drugs daily, there would be over 10^14 possible drug combinations that individual patient could take. It would be impossible to study that many drug combinations.

Yet the polypharmacy is practiced universally and the FDA accepts it. Using the FDA’s own logic, combining various medications together is illegal if the patient swallows all the drugs after they have been compounded into one capsule… but let that same patient individually take the same multiple prescription drugs and swallow them one at a time… then the FDA has no problem with it.

To begin with, some official FDA statements concerning their position on this would be required to support a claim of this nature. MaxEnt 03:12, 9 November 2007 (UTC)

[edit] Disambiguation/title change

A search of "compounding" produces this page, with a link to "compound interest" if that is what you were looking for. There are no pages for "pharmaceutical compounding" or "compounding pharmacy", although this result is first. Considering that "to compound" is a verb with at least three meanings, and pharmaceutical compounding is definitely not the most common usage, it seems that perhaps a title change or disambiguation is necessary. Pamplemousse gnome (talk) 10:08, 19 April 2008 (UTC)