Compartment (pharmacokinetics)

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In pharmacokinetics, a compartment is a defined volume of body fluids. It is distinguished from anatomic compartments, which are bounded by fasciae. It is used in multi-compartment models.

[edit] Examples

There are five major body compartments[1]:

The transcellular compartment includes fluids in the pleural cavity or peritoneal cavity.

[edit] Comparison table

Compartment estimated % of body mass[2]
blood plasma 5
interstitial fluid 16
fat tissue 20 (see also body fat percentage)
intracellular fluid 35
transcellular fluid 2

[edit] References

  1. ^ Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4.  Page 102
  2. ^ Unless else specified in table, then ref s: Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4.  Page 102