Combes quinoline synthesis
From Wikipedia, the free encyclopedia
The Combes quinoline synthesis is a chemical reaction involving the condensation of unsubstituted anilines (1) with β-diketones (2) to form substituted quinolines (4) after an acid-catalyzed ring closure of an intermediate Schiff base (3).[1][2]
[edit] References
- ^ Combes, A. Bull. Chim. Soc. France 1888, 49, 89.
- ^ Bergstrom, F. W. Chem. Rev. 1944, 35, 156. (Review)
[edit] See also
 |
This chemical reaction article is a stub. You can help Wikipedia by expanding it. |
