Collateralization

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In medicine, collateralization, also vessel collaterlization and blood vessel collateralization, is the growth of a blood vessel or several blood vessels that serve the same end organ or vascular bed as another blood vessel that cannot adequately supply that end organ or vascular bed sufficiently.

It is considered a normal response to hypoxia and may be induced, under some circumstances, by exercise. It is considered to be protective.[1]

Contents

[edit] Coronary collateralization

Coronary collateralization is influenced by diabetes mellitus and occlusion of the LAD and acute MI.[2]

[edit] Relation to angiogenesis

Collateraliztion differs from angiogensis in that several blood vessels supply one vascular bed and these vessels are maintained (one does not involute/regress).

[edit] See also

[edit] References

  1. ^ Tayebjee MH, Lip GY, MacFadyen RJ. Collateralization and the response to obstruction of epicardial coronary arteries. QJM. 2004 May;97(5):259-72. Review. PMID 15100419. Free Full Text.
  2. ^ Kilian JG, Keech A, Adams MR, Celermajer DS. Coronary collateralization: determinants of adequate distal vessel filling after arterial occlusion. Coron Artery Dis. 2002 May;13(3):155-9. PMID 12131019.
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